Order Test

Request Price
Test Code B0006
Test Summary

This biochemial test measues the level of creatine kinase.

Turn-Around-Time (TAT)* 3  days
Acceptable Sample Types
Dried Blood Spots
Acceptable Billing Types
Self (patient) Payment
Institutional Billing
*TAT starts after the sample and all required sample information is received at PerkinElmer Genomics, or after the benefits investigation is complete if requested for commercial insurance billing.

This test measures creatine kinase activity, which can be elevated in patients with Duchenne muscular dystrophy (DMD).

Individuals with a clinical suspicion of DMD. Individuals with a family history of DMD

Duchenne muscular dystrophy (DMD) is a inherited muscular dystrophy. DMD usually presents in early childhood with delayed motor milestones. Proximal weakness causes a waddling gait and difficulty climbing stairs, running, jumping and standing up from a squatting position. DMD is progressive with affected children being wheelchair dependent by age 12. Cardiomyopathy occurs in almost all individuals with DMD after age 18. DMD in in herited in an X linked manner. (NCBI, genereviews)

Fluoroimmunometric assay based on the direct sandwich technique in which two antibodies are directed against a given analyte. Calibrators and serum samples, containing the analyte are reacted with immobilized monoclonal antibodies directed against the analyte. Europium-labeled monoclonal antibodies directed against an antigenic site on the analyte are reacted with the analyte bound to the solid-phase antibody.  The Inducer dissociates europium ions from the labeled antibodies into the solution where they form highly fluorescent chelates with components of the Inducer. The fluorescence in each cup is then measured. The europium fluorescence from each sample is proportional to the concentration of analyte in the sample.

Dried Blood Spots
Collection Container(s):

Dried blood spot card

Collection:

Follow kit instructions. Briefly, allow blood to saturate card until indicated areas are filled and blood has soaked through card. Air dry card at ambient temperature for at least 3 hours.

  • NBS: Please contact PKIG to request the StepOne® kit.
  • Gene Sequencing: Please contact PKIG to request the DBS collection kit.
  • For pre-punched DBS: The required minimum 6 punches with 3.2 mm or 4 punches 4.75 mm.
Condition: Follow the instructions provided with the collection set. Store the dried blood at ambient temperature for up to two days. If the specimen cannot be sent as soon as it is dry, the filter paper should be placed in a sealable plastic bag and stored in a refrigerator (≤ 8°C) or preferably in a freezer.
Shipping: Follow kit instructions. Double bag and ship overnight at ambient temperature.

Order Test