About Pre-eclampsia

Most women have a normal pregnancy without complications. However, pre-eclampsia is a relatively common, yet serious complication, affecting between two and eight out of every 100 pregnancies, that may develop during pregnancy (at any time after 20 weeks of pregnancy) and up to six weeks after delivery. It can affect both the pregnant woman and her unborn baby. If the risk for preterm pre-eclampsia is detected in time, the development of the condition can be monitored and prevented.6,7,8
It is important to get screened for the risk of pre-eclampsia as early as possible in the pregnancy to allow adequate time for the doctor managing the pregnancy to ensure that treatment4,7,9 is started at the right time.
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Features of  & Benefits

Features

Accurate predictive screening for pre-eclampsia

Provide risk for preterm pre-eclampsia

Highest detection rate clinically validated

Benefits

High-precision test: Utilizes an accurate DELFIA® technology PlGF assay.

Simple, Safe and Convenient: Reliable results delivered from a single blood draw as early as 11 weeks gestation.

Fast Turn-Around-Time: Results are available in an average of 3-5 days.

Know your risk: Knowing the risk of pre-eclampsia helps your physician/obstetrician to plan, and if needed, adapt treatment.

Test Resources

Burden of Pre-eclampsia in the USA
1st Trimester Pre-eclampsia Screening
Effect of Aspirin in the length of NICU stay
Doctor’s Handbook – Pre-Eclampsia Screening

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Pre-eclampsia FAQs

The test tells you if your pregnancy needs to be monitored more closely and a treatment to be initiated.

Screening for pre-eclampsia is done in the first trimester, preferably between 11 and 13+6 weeks of pregnancy. It includes a simple blood test and your blood pressure is measured. It may also include an ultrasound. In addition health and pregnancy history is needed.

Your risk of developing pre-eclampsia is calculated from the results of simple exams (blood test, blood pressure and ultrasound) and medical information. Based on the calculation results your doctor will adapt your pregnancy management and may suggest preventive care.

If the test result indicates a high risk for preterm pre-eclampsia, research has shown that prophylactic low-dose aspirin treatment may be effective to reduce the onset of pre-eclampsia4,6,7,8; however, because not all women respond the same to aspirin4,9, aspirin intake during pregnancy should only occur after consultation with and advice from your physician/obstetrician.

After 16 weeks of pregnancy, it may be too late to start preventative treatment4,8, but you can still be tested to know your risk of developing the condition. Such information will allow you to discuss options with your doctor.

References

1. Rolnik et al. (2017). NEJM 2017 Supplementary data

2. Masotti et al. (1979). Differential inhibition of prostacyclin production and platelet aggregation by Aspirin. Lancet. 1979 Dec 8;2(8154):1213-7.

3. Mc Nulty et al (2011). Women’s compliance with current folic acid recommendations and achievement of optimal vitamin status for preventing neural tube defects. Human Reproduction. Vol. 26 (June 2011) 6, 1530 -1536.

4. Roberge et al (2017). Aspirin for the prevention of preterm and term preeclampsia: systematic review and metaanalysis. Am J Obstet Gynecol. 2017 Nov 11.

5. Stevens et. al. (2017). Short-term costs of preeclampsia to the United States health care system. AJOG. 2017

6. Rolnik, DL. (2017). ASPRE trial: Performance of screening for pre-term pre-eclampsia. Ultrasound Obstet Gynecol. 2017 Jul 25. doi: 10.1002/uog.18816.

7. Rolnik et al. (2017). Aspirin versus Placebo in Pregnancies at High Risk for pre-term Pre-eclampsia. The New England Journal of Medicine. Vol. 377, 7.

8. Bujold et al. (2010). Obs. & Gyn VOL. 116, NO. 2, PART 1, AUGUST 2010

9. Wertaschnigg et al. (2019). Journal of Pregnancy Volume 2019, Article ID 2675101, 7 pages https://doi.org/10.1155/2019/2675101

PerkinElmer does not endorse or make recommendations with respect to research, medication, or treatments. All information presented is for informational purposes only and is not intended as medical advice. For country specific recommendations please consult your local health care professionals.

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